Composition
Each 5ml contains:
Sucralfate 1gm
Oxetacaine 10mg

Mechanism of Action
Sucralfate
• Attaches to the exposed proteins on the surface of ulcers such as albumin and fibrinogen.
• Forms stable insoluble complexes.
• Coats the ulcer & forms the protective layer.
• Prevents further injury by acid, pepsin & bile.
• Binds directly with pepsin and bile salt & protects the stomach lining from injury.
• Stimulates gastric bicarbonate secretion.
• Promotes ulcer healing.
Oxetacaine
• It is a local anaesthetic of the amide type.
• It produces a reversible loss of sensation by preventing or diminishing the conduction of sensory nerve impulses near the site of its application.
• It decreases the permeability of the nerve cell membrane to sodium ions by membrane stabilising effect.
• Relieves pain, bloating,discomfort, and fullness

Indications
It is used for the symptomatic treatment of ulcer & pain in Gastric Ulcer, Duodenal Ulcer, Gastritis, G.E.R.D

Contraindications
Contraindicated in patients with proven allergy to any ingredient

Special Precautions
Systemic AI toxicity may occur in patients with chronic renal failure. Neonates, children; pregnancy and lactation.


Interaction
Avoid antacids within 30 minutes of sucralcoat administration. May reduce absorption of tetracyclines, ranitidine, ketoconazole, theophylline, phenytoin, cimetidine & digoxin (ensure a dosing interval of at least 2 hr. between administration of sucralcoat & other non-antacid medications)

Adverse Drug Reactions
Constipation, diarrhea, nausea, dizziness, dry mouth, GI disturbances, rash, pruritis, headache, vertigo, back pain & drowsiness, Nervousness, Blurred vision.


Dosage
5ml four times daily on an empty stomach, one hour before each meal and at bed time.


Packing
Bottle Pack of 100 ml Suspension.